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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NEGHOLOK_00011	9.06e-44	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NEGHOLOK_00021	2.58e-69	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
NEGHOLOK_00024	2.03e-38	-	-	-	L	-	-	-	Mu-like prophage protein gp29
NEGHOLOK_00025	5.05e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
NEGHOLOK_00032	1.49e-08	-	-	-	-	-	-	-	-
NEGHOLOK_00036	1.99e-138	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
NEGHOLOK_00044	4.61e-55	-	-	-	S	-	-	-	AAA domain
NEGHOLOK_00048	9.41e-72	-	-	-	KT	-	-	-	Peptidase S24-like
NEGHOLOK_00055	2.58e-28	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_00057	3.35e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEGHOLOK_00058	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
NEGHOLOK_00059	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEGHOLOK_00060	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NEGHOLOK_00061	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NEGHOLOK_00062	6.98e-80	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
NEGHOLOK_00063	3.6e-243	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEGHOLOK_00064	3.81e-129	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEGHOLOK_00065	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
NEGHOLOK_00068	1.6e-215	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
NEGHOLOK_00069	6.23e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
NEGHOLOK_00070	1.62e-65	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NEGHOLOK_00071	5.68e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEGHOLOK_00072	2.45e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
NEGHOLOK_00073	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
NEGHOLOK_00074	2.43e-126	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
NEGHOLOK_00075	1.91e-204	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
NEGHOLOK_00076	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
NEGHOLOK_00082	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NEGHOLOK_00083	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NEGHOLOK_00084	2.73e-263	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
NEGHOLOK_00085	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
NEGHOLOK_00086	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEGHOLOK_00087	3.74e-204	-	-	-	-	-	-	-	-
NEGHOLOK_00088	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEGHOLOK_00089	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEGHOLOK_00090	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
NEGHOLOK_00091	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEGHOLOK_00092	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEGHOLOK_00093	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
NEGHOLOK_00094	4.05e-152	-	-	-	-	-	-	-	-
NEGHOLOK_00095	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEGHOLOK_00096	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEGHOLOK_00097	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEGHOLOK_00098	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
NEGHOLOK_00099	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEGHOLOK_00100	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
NEGHOLOK_00101	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEGHOLOK_00102	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
NEGHOLOK_00103	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
NEGHOLOK_00104	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
NEGHOLOK_00105	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
NEGHOLOK_00106	1.82e-274	-	-	-	T	-	-	-	PAS domain
NEGHOLOK_00107	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
NEGHOLOK_00108	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
NEGHOLOK_00109	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
NEGHOLOK_00110	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEGHOLOK_00111	3.99e-183	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_00112	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
NEGHOLOK_00113	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
NEGHOLOK_00114	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
NEGHOLOK_00115	1.24e-230	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NEGHOLOK_00117	1.78e-154	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
NEGHOLOK_00119	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NEGHOLOK_00120	2.88e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_00121	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
NEGHOLOK_00122	1.46e-204	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
NEGHOLOK_00124	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
NEGHOLOK_00125	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
NEGHOLOK_00127	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
NEGHOLOK_00128	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
NEGHOLOK_00129	3.99e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEGHOLOK_00130	2.75e-142	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
NEGHOLOK_00131	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEGHOLOK_00132	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEGHOLOK_00133	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEGHOLOK_00135	2.13e-256	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NEGHOLOK_00136	1.25e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
NEGHOLOK_00139	7.55e-302	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
NEGHOLOK_00143	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NEGHOLOK_00146	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
NEGHOLOK_00147	8.38e-98	-	-	-	-	-	-	-	-
NEGHOLOK_00148	9e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NEGHOLOK_00149	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
NEGHOLOK_00150	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
NEGHOLOK_00151	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
NEGHOLOK_00152	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NEGHOLOK_00154	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_00156	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_00157	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
NEGHOLOK_00159	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NEGHOLOK_00160	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
NEGHOLOK_00161	1.22e-237	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
NEGHOLOK_00162	4.34e-152	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
NEGHOLOK_00163	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEGHOLOK_00164	2.31e-164	-	-	-	CO	-	-	-	Thioredoxin-like
NEGHOLOK_00165	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
NEGHOLOK_00166	1.88e-308	-	-	-	S	-	-	-	PFAM CBS domain containing protein
NEGHOLOK_00167	2.59e-312	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
NEGHOLOK_00168	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEGHOLOK_00169	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
NEGHOLOK_00170	8.11e-152	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NEGHOLOK_00171	1.94e-212	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
NEGHOLOK_00172	0.0	-	-	-	S	-	-	-	Terminase
NEGHOLOK_00175	2.16e-200	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEGHOLOK_00176	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEGHOLOK_00177	4.02e-167	-	-	-	M	-	-	-	Peptidase family M23
NEGHOLOK_00178	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
NEGHOLOK_00180	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
NEGHOLOK_00182	9.93e-180	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NEGHOLOK_00183	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
NEGHOLOK_00184	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
NEGHOLOK_00185	6.94e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
NEGHOLOK_00187	4.86e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
NEGHOLOK_00188	2.97e-142	-	-	-	-	-	-	-	-
NEGHOLOK_00189	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_00190	8.39e-197	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NEGHOLOK_00191	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
NEGHOLOK_00192	2.31e-187	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NEGHOLOK_00193	8.12e-195	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEGHOLOK_00194	1.63e-189	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_00195	3.92e-247	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
NEGHOLOK_00197	8.93e-223	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
NEGHOLOK_00198	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
NEGHOLOK_00199	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
NEGHOLOK_00200	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
NEGHOLOK_00201	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
NEGHOLOK_00202	3.01e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NEGHOLOK_00203	1.39e-258	-	-	-	S	-	-	-	ankyrin repeats
NEGHOLOK_00204	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NEGHOLOK_00205	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_00206	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
NEGHOLOK_00207	9.59e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
NEGHOLOK_00208	1.48e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEGHOLOK_00209	4.7e-205	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEGHOLOK_00210	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
NEGHOLOK_00211	1.07e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
NEGHOLOK_00212	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
NEGHOLOK_00213	3.76e-181	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
NEGHOLOK_00214	6.87e-153	-	-	-	O	-	-	-	methyltransferase activity
NEGHOLOK_00215	6.9e-288	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
NEGHOLOK_00216	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
NEGHOLOK_00217	1.07e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NEGHOLOK_00221	1.99e-191	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NEGHOLOK_00222	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
NEGHOLOK_00223	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEGHOLOK_00224	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEGHOLOK_00225	3.9e-270	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
NEGHOLOK_00226	1.96e-223	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
NEGHOLOK_00227	2.1e-269	-	-	-	M	-	-	-	Glycosyl transferase 4-like
NEGHOLOK_00228	3.24e-271	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NEGHOLOK_00229	4.25e-219	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NEGHOLOK_00230	5.5e-262	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEGHOLOK_00231	4.93e-268	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
NEGHOLOK_00232	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NEGHOLOK_00233	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NEGHOLOK_00235	6.98e-156	-	-	-	L	-	-	-	Membrane
NEGHOLOK_00236	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
NEGHOLOK_00237	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
NEGHOLOK_00238	6.16e-176	-	-	-	-	-	-	-	-
NEGHOLOK_00239	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
NEGHOLOK_00240	1.41e-242	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NEGHOLOK_00241	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
NEGHOLOK_00242	4.07e-246	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
NEGHOLOK_00243	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEGHOLOK_00244	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
NEGHOLOK_00246	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NEGHOLOK_00247	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
NEGHOLOK_00248	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
NEGHOLOK_00250	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
NEGHOLOK_00251	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NEGHOLOK_00252	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
NEGHOLOK_00253	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NEGHOLOK_00254	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
NEGHOLOK_00255	9.7e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
NEGHOLOK_00256	8.3e-158	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
NEGHOLOK_00257	1.67e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEGHOLOK_00258	5.45e-232	-	-	-	S	-	-	-	Aspartyl protease
NEGHOLOK_00259	4.79e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
NEGHOLOK_00260	2.75e-130	-	-	-	L	-	-	-	Conserved hypothetical protein 95
NEGHOLOK_00261	2.84e-211	-	-	-	-	-	-	-	-
NEGHOLOK_00263	4.28e-224	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NEGHOLOK_00264	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_00265	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NEGHOLOK_00267	6.18e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
NEGHOLOK_00268	6.74e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NEGHOLOK_00269	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
NEGHOLOK_00270	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
NEGHOLOK_00271	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
NEGHOLOK_00272	1.24e-179	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_00273	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
NEGHOLOK_00274	9.06e-297	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
NEGHOLOK_00275	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
NEGHOLOK_00276	0.0	-	-	-	P	-	-	-	Sulfatase
NEGHOLOK_00277	2.93e-233	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
NEGHOLOK_00278	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NEGHOLOK_00279	3.63e-135	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NEGHOLOK_00282	3.2e-76	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
NEGHOLOK_00283	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
NEGHOLOK_00284	6.54e-221	-	-	-	M	-	-	-	Glycosyl transferase family 2
NEGHOLOK_00285	2.98e-115	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEGHOLOK_00286	2.94e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NEGHOLOK_00287	2.58e-276	-	-	-	S	-	-	-	COGs COG4299 conserved
NEGHOLOK_00288	7.66e-124	sprT	-	-	K	-	-	-	SprT-like family
NEGHOLOK_00289	1.38e-139	-	-	-	-	-	-	-	-
NEGHOLOK_00290	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NEGHOLOK_00291	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEGHOLOK_00292	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEGHOLOK_00293	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEGHOLOK_00294	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
NEGHOLOK_00295	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
NEGHOLOK_00296	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
NEGHOLOK_00297	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
NEGHOLOK_00298	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_00299	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
NEGHOLOK_00300	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEGHOLOK_00301	3.11e-271	-	-	-	S	-	-	-	COGs COG4299 conserved
NEGHOLOK_00302	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
NEGHOLOK_00304	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEGHOLOK_00305	8.29e-223	-	-	-	-	-	-	-	-
NEGHOLOK_00306	7.33e-110	-	-	-	U	-	-	-	response to pH
NEGHOLOK_00307	9.39e-183	-	-	-	H	-	-	-	ThiF family
NEGHOLOK_00308	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
NEGHOLOK_00309	1.91e-192	-	-	-	-	-	-	-	-
NEGHOLOK_00310	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
NEGHOLOK_00311	3.05e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
NEGHOLOK_00312	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
NEGHOLOK_00313	2.46e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEGHOLOK_00314	1.25e-179	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEGHOLOK_00315	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEGHOLOK_00316	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
NEGHOLOK_00317	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
NEGHOLOK_00318	6.74e-117	-	-	-	-	-	-	-	-
NEGHOLOK_00319	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
NEGHOLOK_00320	1.3e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NEGHOLOK_00322	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
NEGHOLOK_00324	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
NEGHOLOK_00325	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
NEGHOLOK_00326	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
NEGHOLOK_00327	8.99e-277	-	-	-	K	-	-	-	sequence-specific DNA binding
NEGHOLOK_00328	1.28e-193	-	-	-	-	-	-	-	-
NEGHOLOK_00329	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_00331	4.52e-101	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
NEGHOLOK_00332	1.65e-113	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
NEGHOLOK_00333	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NEGHOLOK_00334	8.42e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEGHOLOK_00335	1.39e-157	-	-	-	S	-	-	-	3D domain
NEGHOLOK_00336	5.64e-228	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
NEGHOLOK_00337	4.1e-178	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
NEGHOLOK_00339	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
NEGHOLOK_00340	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
NEGHOLOK_00341	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
NEGHOLOK_00342	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
NEGHOLOK_00343	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEGHOLOK_00345	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
NEGHOLOK_00346	1.05e-115	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
NEGHOLOK_00347	8.12e-302	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
NEGHOLOK_00348	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEGHOLOK_00349	9.08e-165	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NEGHOLOK_00350	7.54e-143	-	-	-	-	-	-	-	-
NEGHOLOK_00351	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
NEGHOLOK_00355	2.03e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
NEGHOLOK_00356	1.19e-180	-	-	-	S	-	-	-	competence protein
NEGHOLOK_00357	2.92e-70	-	-	-	-	-	-	-	-
NEGHOLOK_00358	4.15e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
NEGHOLOK_00359	3.68e-75	-	-	-	-	-	-	-	-
NEGHOLOK_00360	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NEGHOLOK_00362	4.56e-139	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
NEGHOLOK_00363	2.22e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
NEGHOLOK_00364	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
NEGHOLOK_00365	5.63e-78	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NEGHOLOK_00366	1.01e-151	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_00367	2.59e-134	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	5,10-methylenetetrahydrofolate reductase
NEGHOLOK_00368	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEGHOLOK_00369	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
NEGHOLOK_00371	1.3e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NEGHOLOK_00372	1.76e-175	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
NEGHOLOK_00373	1.88e-136	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NEGHOLOK_00374	0.0	-	-	-	S	-	-	-	pathogenesis
NEGHOLOK_00375	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
NEGHOLOK_00377	2.22e-231	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NEGHOLOK_00378	2.5e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
NEGHOLOK_00379	6.76e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NEGHOLOK_00380	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NEGHOLOK_00381	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NEGHOLOK_00383	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NEGHOLOK_00384	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
NEGHOLOK_00386	5.7e-07	-	-	-	-	-	-	-	-
NEGHOLOK_00387	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
NEGHOLOK_00388	2.53e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
NEGHOLOK_00389	1.78e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NEGHOLOK_00390	2.63e-84	-	-	-	M	-	-	-	Lysin motif
NEGHOLOK_00391	8.74e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEGHOLOK_00392	0.0	-	-	-	V	-	-	-	MatE
NEGHOLOK_00393	1.05e-252	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
NEGHOLOK_00395	1.45e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEGHOLOK_00397	1.63e-156	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
NEGHOLOK_00398	2.07e-262	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
NEGHOLOK_00399	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEGHOLOK_00400	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
NEGHOLOK_00401	0.0	-	-	-	O	-	-	-	Trypsin
NEGHOLOK_00402	1.18e-109	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NEGHOLOK_00403	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
NEGHOLOK_00404	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NEGHOLOK_00405	0.0	-	-	-	P	-	-	-	Cation transport protein
NEGHOLOK_00406	8.16e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
NEGHOLOK_00407	4.33e-17	-	-	-	K	-	-	-	Helix-turn-helix domain
NEGHOLOK_00409	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEGHOLOK_00410	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
NEGHOLOK_00411	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NEGHOLOK_00412	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
NEGHOLOK_00413	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NEGHOLOK_00414	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
NEGHOLOK_00415	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
NEGHOLOK_00416	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
NEGHOLOK_00417	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NEGHOLOK_00418	8.62e-102	-	-	-	-	-	-	-	-
NEGHOLOK_00420	1.99e-263	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
NEGHOLOK_00421	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
NEGHOLOK_00422	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NEGHOLOK_00423	4.94e-05	-	-	-	-	-	-	-	-
NEGHOLOK_00424	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
NEGHOLOK_00425	2.36e-209	-	-	-	S	-	-	-	Rhomboid family
NEGHOLOK_00426	2.63e-269	-	-	-	E	-	-	-	FAD dependent oxidoreductase
NEGHOLOK_00427	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEGHOLOK_00430	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
NEGHOLOK_00431	2e-120	-	-	-	K	-	-	-	ParB domain protein nuclease
NEGHOLOK_00434	9.17e-116	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
NEGHOLOK_00435	5.62e-247	-	-	-	M	-	-	-	Alginate lyase
NEGHOLOK_00436	1.79e-206	-	-	-	IQ	-	-	-	KR domain
NEGHOLOK_00439	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
NEGHOLOK_00440	1.42e-315	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
NEGHOLOK_00441	1.72e-290	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NEGHOLOK_00442	1.38e-241	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEGHOLOK_00443	1.3e-180	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEGHOLOK_00444	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
NEGHOLOK_00446	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
NEGHOLOK_00447	0.0	-	-	-	E	-	-	-	Transglutaminase-like
NEGHOLOK_00448	6.8e-111	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
NEGHOLOK_00449	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
NEGHOLOK_00451	0.0	-	-	-	P	-	-	-	Citrate transporter
NEGHOLOK_00453	8.04e-258	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
NEGHOLOK_00454	0.0	-	-	-	I	-	-	-	Acyltransferase family
NEGHOLOK_00455	1.74e-251	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
NEGHOLOK_00456	7.13e-310	-	-	-	M	-	-	-	Glycosyl transferases group 1
NEGHOLOK_00457	1.03e-204	-	-	-	-	-	-	-	-
NEGHOLOK_00458	2.25e-287	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEGHOLOK_00459	2.26e-245	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
NEGHOLOK_00460	3.86e-235	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
NEGHOLOK_00461	6.79e-249	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NEGHOLOK_00462	4.53e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
NEGHOLOK_00463	4.39e-209	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
NEGHOLOK_00465	7.27e-242	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
NEGHOLOK_00466	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEGHOLOK_00467	2.87e-219	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
NEGHOLOK_00468	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NEGHOLOK_00469	8.9e-82	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NEGHOLOK_00470	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NEGHOLOK_00471	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEGHOLOK_00472	1.06e-127	-	-	-	-	-	-	-	-
NEGHOLOK_00473	1.02e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NEGHOLOK_00474	2.89e-173	-	-	-	S	-	-	-	NYN domain
NEGHOLOK_00475	2.15e-151	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
NEGHOLOK_00476	1.58e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
NEGHOLOK_00477	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
NEGHOLOK_00478	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
NEGHOLOK_00479	1.43e-120	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NEGHOLOK_00480	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NEGHOLOK_00482	5.94e-266	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
NEGHOLOK_00483	1.81e-253	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NEGHOLOK_00484	8.14e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NEGHOLOK_00485	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEGHOLOK_00487	7.86e-138	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
NEGHOLOK_00488	1.39e-130	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NEGHOLOK_00489	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
NEGHOLOK_00490	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NEGHOLOK_00491	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NEGHOLOK_00492	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NEGHOLOK_00493	3.97e-313	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
NEGHOLOK_00494	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
NEGHOLOK_00495	1.98e-156	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
NEGHOLOK_00496	1.14e-294	-	-	-	E	-	-	-	Amino acid permease
NEGHOLOK_00497	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
NEGHOLOK_00499	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
NEGHOLOK_00500	7.86e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEGHOLOK_00502	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
NEGHOLOK_00503	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
NEGHOLOK_00504	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
NEGHOLOK_00505	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEGHOLOK_00506	4.88e-169	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NEGHOLOK_00507	2.69e-181	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
NEGHOLOK_00508	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEGHOLOK_00509	2.2e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
NEGHOLOK_00510	6.99e-238	-	-	-	E	-	-	-	Aminotransferase class-V
NEGHOLOK_00511	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NEGHOLOK_00512	2.58e-214	-	-	-	K	-	-	-	LysR substrate binding domain
NEGHOLOK_00515	6.92e-288	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NEGHOLOK_00516	1.31e-153	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NEGHOLOK_00517	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
NEGHOLOK_00518	2.41e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
NEGHOLOK_00519	1.98e-261	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEGHOLOK_00520	2.49e-157	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NEGHOLOK_00522	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
NEGHOLOK_00523	5.48e-296	-	-	-	-	-	-	-	-
NEGHOLOK_00524	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
NEGHOLOK_00526	0.0	-	-	-	T	-	-	-	pathogenesis
NEGHOLOK_00527	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEGHOLOK_00528	4.38e-113	ywrF	-	-	S	-	-	-	FMN binding
NEGHOLOK_00529	2.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NEGHOLOK_00530	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
NEGHOLOK_00531	1.27e-305	-	-	-	M	-	-	-	OmpA family
NEGHOLOK_00532	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
NEGHOLOK_00533	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
NEGHOLOK_00534	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_00537	2.72e-197	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
NEGHOLOK_00538	1.86e-171	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
NEGHOLOK_00539	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
NEGHOLOK_00540	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEGHOLOK_00541	7.6e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
NEGHOLOK_00543	7.19e-281	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
NEGHOLOK_00544	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NEGHOLOK_00545	0.0	-	-	-	O	-	-	-	Trypsin
NEGHOLOK_00546	4.99e-274	-	-	-	-	-	-	-	-
NEGHOLOK_00547	3.6e-145	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
NEGHOLOK_00548	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
NEGHOLOK_00549	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NEGHOLOK_00550	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
NEGHOLOK_00551	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEGHOLOK_00552	2.1e-215	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
NEGHOLOK_00553	4.13e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
NEGHOLOK_00554	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
NEGHOLOK_00555	5.55e-267	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEGHOLOK_00556	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
NEGHOLOK_00557	1e-160	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
NEGHOLOK_00558	1.45e-314	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEGHOLOK_00559	8.1e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEGHOLOK_00560	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
NEGHOLOK_00561	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEGHOLOK_00562	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
NEGHOLOK_00564	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEGHOLOK_00565	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NEGHOLOK_00566	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NEGHOLOK_00567	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
NEGHOLOK_00568	3.95e-13	-	-	-	S	-	-	-	Mac 1
NEGHOLOK_00569	8.07e-314	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEGHOLOK_00570	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEGHOLOK_00571	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
NEGHOLOK_00572	1.47e-208	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEGHOLOK_00573	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NEGHOLOK_00574	1.04e-272	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NEGHOLOK_00575	8.79e-143	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
NEGHOLOK_00576	1.64e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
NEGHOLOK_00577	6.99e-290	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEGHOLOK_00578	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
NEGHOLOK_00580	1.36e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
NEGHOLOK_00581	1.5e-254	-	-	-	M	-	-	-	Glycosyl transferase, family 2
NEGHOLOK_00582	1.98e-259	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
NEGHOLOK_00583	1.29e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NEGHOLOK_00584	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEGHOLOK_00585	5.47e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEGHOLOK_00588	1e-116	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
NEGHOLOK_00589	1.43e-63	-	-	-	L	-	-	-	PFAM Restriction endonuclease, type II, HindVP
NEGHOLOK_00592	4.82e-25	-	-	-	V	-	-	-	HNH endonuclease
NEGHOLOK_00593	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
NEGHOLOK_00594	1.19e-315	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
NEGHOLOK_00595	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
NEGHOLOK_00596	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
NEGHOLOK_00597	1.05e-79	-	-	-	Q	-	-	-	methyltransferase activity
NEGHOLOK_00598	7.99e-75	-	-	-	Q	-	-	-	methyltransferase activity
NEGHOLOK_00600	4.82e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
NEGHOLOK_00601	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NEGHOLOK_00602	6.13e-194	-	-	-	-	-	-	-	-
NEGHOLOK_00603	1.41e-120	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
NEGHOLOK_00604	6.3e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
NEGHOLOK_00605	2.88e-116	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
NEGHOLOK_00606	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
NEGHOLOK_00607	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
NEGHOLOK_00608	1.19e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
NEGHOLOK_00609	3.77e-181	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NEGHOLOK_00610	2.72e-18	-	-	-	-	-	-	-	-
NEGHOLOK_00611	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
NEGHOLOK_00612	2.4e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEGHOLOK_00613	2.54e-39	-	-	-	V	-	-	-	Abi-like protein
NEGHOLOK_00614	3.15e-121	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
NEGHOLOK_00615	9.06e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEGHOLOK_00616	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NEGHOLOK_00617	2.8e-143	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
NEGHOLOK_00618	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
NEGHOLOK_00619	4.91e-209	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NEGHOLOK_00620	1.77e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NEGHOLOK_00621	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
NEGHOLOK_00622	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NEGHOLOK_00624	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEGHOLOK_00625	1.37e-129	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
NEGHOLOK_00626	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NEGHOLOK_00635	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEGHOLOK_00636	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
NEGHOLOK_00637	2.66e-147	-	-	-	C	-	-	-	lactate oxidation
NEGHOLOK_00638	1.02e-296	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
NEGHOLOK_00639	1.99e-19	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
NEGHOLOK_00640	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
NEGHOLOK_00641	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
NEGHOLOK_00642	1.39e-281	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
NEGHOLOK_00644	3.97e-153	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
NEGHOLOK_00645	4.85e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEGHOLOK_00646	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEGHOLOK_00647	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEGHOLOK_00648	9.14e-223	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
NEGHOLOK_00649	4.49e-186	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEGHOLOK_00650	4.97e-138	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
NEGHOLOK_00651	6.15e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NEGHOLOK_00652	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
NEGHOLOK_00654	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
NEGHOLOK_00655	4.72e-153	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NEGHOLOK_00656	2.74e-95	-	-	-	S	-	-	-	Maltose acetyltransferase
NEGHOLOK_00657	5.03e-229	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
NEGHOLOK_00658	4.31e-231	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
NEGHOLOK_00659	1.7e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NEGHOLOK_00660	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
NEGHOLOK_00661	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEGHOLOK_00662	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
NEGHOLOK_00663	2.94e-208	-	-	-	M	-	-	-	Mechanosensitive ion channel
NEGHOLOK_00664	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NEGHOLOK_00665	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
NEGHOLOK_00666	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_00667	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEGHOLOK_00668	3.08e-146	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEGHOLOK_00670	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEGHOLOK_00672	4.86e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
NEGHOLOK_00673	7.19e-260	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEGHOLOK_00674	1.16e-301	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
NEGHOLOK_00677	3.08e-246	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEGHOLOK_00678	1.2e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEGHOLOK_00679	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_00680	5.59e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
NEGHOLOK_00681	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEGHOLOK_00682	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
NEGHOLOK_00683	4.03e-120	-	-	-	-	-	-	-	-
NEGHOLOK_00684	8.75e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NEGHOLOK_00685	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
NEGHOLOK_00686	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
NEGHOLOK_00687	9.4e-148	-	-	-	IQ	-	-	-	RmlD substrate binding domain
NEGHOLOK_00688	4.38e-286	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NEGHOLOK_00689	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
NEGHOLOK_00690	5.11e-285	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
NEGHOLOK_00691	4.02e-262	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NEGHOLOK_00696	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NEGHOLOK_00697	7.37e-311	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
NEGHOLOK_00698	1.44e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
NEGHOLOK_00699	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
NEGHOLOK_00700	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
NEGHOLOK_00701	3.17e-261	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
NEGHOLOK_00702	1.71e-239	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
NEGHOLOK_00703	4.65e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
NEGHOLOK_00704	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NEGHOLOK_00705	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
NEGHOLOK_00706	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEGHOLOK_00707	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEGHOLOK_00708	5.31e-99	-	-	-	S	-	-	-	peptidase
NEGHOLOK_00709	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
NEGHOLOK_00713	8.04e-298	-	-	-	-	-	-	-	-
NEGHOLOK_00714	0.0	-	-	-	D	-	-	-	Chain length determinant protein
NEGHOLOK_00715	3.37e-133	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
NEGHOLOK_00717	1.09e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEGHOLOK_00718	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
NEGHOLOK_00719	1.36e-284	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NEGHOLOK_00720	2.58e-234	-	-	-	-	-	-	-	-
NEGHOLOK_00721	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
NEGHOLOK_00722	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
NEGHOLOK_00723	0.0	-	-	-	L	-	-	-	TRCF
NEGHOLOK_00724	3.12e-294	-	-	-	-	-	-	-	-
NEGHOLOK_00725	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEGHOLOK_00726	1e-252	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NEGHOLOK_00728	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
NEGHOLOK_00729	1.63e-258	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
NEGHOLOK_00730	4.05e-242	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEGHOLOK_00731	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NEGHOLOK_00735	1.89e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
NEGHOLOK_00739	9.45e-317	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
NEGHOLOK_00740	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
NEGHOLOK_00741	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
NEGHOLOK_00742	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
NEGHOLOK_00743	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NEGHOLOK_00744	1.51e-152	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
NEGHOLOK_00745	1.07e-192	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NEGHOLOK_00746	3.17e-171	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NEGHOLOK_00747	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_00748	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
NEGHOLOK_00749	1.77e-166	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NEGHOLOK_00750	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NEGHOLOK_00752	1.44e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
NEGHOLOK_00753	2.26e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEGHOLOK_00754	3.39e-109	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
NEGHOLOK_00755	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
NEGHOLOK_00757	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
NEGHOLOK_00758	2.41e-148	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
NEGHOLOK_00759	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
NEGHOLOK_00760	7.06e-249	-	-	-	-	-	-	-	-
NEGHOLOK_00762	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
NEGHOLOK_00763	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
NEGHOLOK_00764	1.16e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEGHOLOK_00765	1.2e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEGHOLOK_00766	1.34e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEGHOLOK_00767	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NEGHOLOK_00768	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NEGHOLOK_00769	1.02e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
NEGHOLOK_00770	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
NEGHOLOK_00771	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
NEGHOLOK_00772	6.29e-151	-	-	-	-	-	-	-	-
NEGHOLOK_00773	5.95e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
NEGHOLOK_00774	1.76e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
NEGHOLOK_00775	1.19e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
NEGHOLOK_00776	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEGHOLOK_00777	1.51e-132	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEGHOLOK_00779	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
NEGHOLOK_00780	6.22e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEGHOLOK_00781	6.37e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
NEGHOLOK_00782	4.4e-212	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
NEGHOLOK_00785	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
NEGHOLOK_00786	9e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
NEGHOLOK_00787	4.82e-220	-	-	-	L	-	-	-	Membrane
NEGHOLOK_00788	1.52e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
NEGHOLOK_00789	9.1e-237	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
NEGHOLOK_00792	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NEGHOLOK_00793	4.1e-193	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
NEGHOLOK_00794	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
NEGHOLOK_00795	0.0	-	-	-	P	-	-	-	Citrate transporter
NEGHOLOK_00796	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
NEGHOLOK_00799	3.1e-217	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NEGHOLOK_00800	4.49e-169	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
NEGHOLOK_00802	1.12e-217	-	-	-	-	-	-	-	-
NEGHOLOK_00803	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
NEGHOLOK_00804	1.28e-172	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
NEGHOLOK_00805	9.72e-227	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NEGHOLOK_00806	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NEGHOLOK_00808	3.26e-278	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
NEGHOLOK_00809	1.38e-257	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
NEGHOLOK_00810	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGHOLOK_00811	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NEGHOLOK_00812	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
NEGHOLOK_00814	6.65e-169	-	-	-	S	-	-	-	HAD-hyrolase-like
NEGHOLOK_00815	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
NEGHOLOK_00816	3.63e-270	-	-	-	E	-	-	-	serine-type peptidase activity
NEGHOLOK_00817	1.85e-304	-	-	-	M	-	-	-	OmpA family
NEGHOLOK_00818	7.32e-215	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NEGHOLOK_00819	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
NEGHOLOK_00820	9.77e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NEGHOLOK_00821	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
NEGHOLOK_00822	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
NEGHOLOK_00823	1.16e-242	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NEGHOLOK_00824	3.26e-173	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
NEGHOLOK_00825	9.06e-189	-	-	-	-	-	-	-	-
NEGHOLOK_00826	7.31e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NEGHOLOK_00827	6.92e-183	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NEGHOLOK_00828	4.06e-244	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NEGHOLOK_00829	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
NEGHOLOK_00833	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
NEGHOLOK_00834	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEGHOLOK_00835	1.67e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
NEGHOLOK_00836	2.94e-155	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
NEGHOLOK_00837	3.6e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEGHOLOK_00838	5.46e-188	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEGHOLOK_00840	0.0	-	-	-	T	-	-	-	pathogenesis
NEGHOLOK_00841	6.2e-89	-	-	-	O	-	-	-	response to oxidative stress
NEGHOLOK_00843	5.79e-31	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEGHOLOK_00844	3.97e-07	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NEGHOLOK_00847	4.15e-287	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
NEGHOLOK_00848	1.08e-63	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
NEGHOLOK_00849	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
NEGHOLOK_00850	1.35e-191	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
NEGHOLOK_00851	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NEGHOLOK_00852	8.08e-189	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
NEGHOLOK_00853	5.24e-186	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
NEGHOLOK_00854	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
NEGHOLOK_00855	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
NEGHOLOK_00856	3.79e-195	supH	-	-	Q	-	-	-	phosphatase activity
NEGHOLOK_00858	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_00859	4.12e-275	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEGHOLOK_00860	2.78e-05	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_00862	6e-37	-	-	-	K	-	-	-	sequence-specific DNA binding
NEGHOLOK_00863	3.04e-167	-	-	-	S	-	-	-	Pfam:HipA_N
NEGHOLOK_00864	4.84e-36	-	-	-	S	-	-	-	zeta toxin
NEGHOLOK_00871	3.73e-45	-	-	-	L	-	-	-	Domain of unknown function (DUF932)
NEGHOLOK_00873	0.0	hsdR	-	-	V	-	-	-	Subunit R is required for both nuclease and ATPase activities, but not for modification
NEGHOLOK_00874	5.66e-27	-	-	-	DK	-	-	-	Fic/DOC family
NEGHOLOK_00875	8e-101	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NEGHOLOK_00876	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NEGHOLOK_00877	2.63e-101	-	-	-	L	ko:K07448	-	ko00000,ko02048	HB1, ASXL, restriction endonuclease HTH domain
NEGHOLOK_00878	1.58e-92	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NEGHOLOK_00879	5.53e-40	-	-	-	-	-	-	-	-
NEGHOLOK_00882	7.55e-05	-	-	-	S	-	-	-	TM2 domain
NEGHOLOK_00889	1.07e-58	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
NEGHOLOK_00890	7.44e-125	-	-	-	S	-	-	-	Virulence protein RhuM family
NEGHOLOK_00891	1.29e-161	-	-	-	K	-	-	-	filamentation induced by cAMP protein Fic
NEGHOLOK_00892	9.51e-27	-	-	-	V	-	-	-	Restriction endonuclease
NEGHOLOK_00893	6.29e-41	-	-	-	S	-	-	-	von Willebrand factor type A domain
NEGHOLOK_00894	1.53e-07	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
NEGHOLOK_00895	6.22e-74	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NEGHOLOK_00896	1.58e-117	-	-	-	S	-	-	-	nitrogen fixation
NEGHOLOK_00897	1.58e-148	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
NEGHOLOK_00898	2.36e-269	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NEGHOLOK_00899	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NEGHOLOK_00900	7.09e-253	-	-	-	L	-	-	-	Transposase IS200 like
NEGHOLOK_00901	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NEGHOLOK_00902	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NEGHOLOK_00905	1.59e-150	-	-	-	-	-	-	-	-
NEGHOLOK_00906	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NEGHOLOK_00908	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
NEGHOLOK_00909	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEGHOLOK_00910	2.24e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEGHOLOK_00911	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
NEGHOLOK_00912	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
NEGHOLOK_00913	2.77e-41	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
NEGHOLOK_00914	2.49e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
NEGHOLOK_00915	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
NEGHOLOK_00916	0.0	-	-	-	V	-	-	-	T5orf172
NEGHOLOK_00917	2.04e-198	-	-	-	L	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NEGHOLOK_00918	9.13e-63	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
NEGHOLOK_00919	6.33e-74	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_00920	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
NEGHOLOK_00921	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
NEGHOLOK_00922	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
NEGHOLOK_00923	5.02e-115	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
NEGHOLOK_00924	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
NEGHOLOK_00925	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
NEGHOLOK_00926	4.85e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NEGHOLOK_00928	1.53e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
NEGHOLOK_00929	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NEGHOLOK_00930	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
NEGHOLOK_00931	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NEGHOLOK_00932	4.02e-121	-	-	-	-	-	-	-	-
NEGHOLOK_00933	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
NEGHOLOK_00934	1.56e-113	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
NEGHOLOK_00935	2.43e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
NEGHOLOK_00936	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_00937	2.36e-291	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_00939	4.27e-117	gepA	-	-	K	-	-	-	Phage-associated protein
NEGHOLOK_00940	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEGHOLOK_00941	8.4e-136	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEGHOLOK_00942	1.86e-214	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NEGHOLOK_00943	2.89e-310	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NEGHOLOK_00944	2.55e-102	-	-	-	K	-	-	-	Transcriptional regulator
NEGHOLOK_00945	1.6e-272	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEGHOLOK_00946	2.84e-173	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
NEGHOLOK_00947	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
NEGHOLOK_00948	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
NEGHOLOK_00949	1.35e-284	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
NEGHOLOK_00950	1.16e-240	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
NEGHOLOK_00951	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
NEGHOLOK_00952	4.29e-256	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
NEGHOLOK_00953	1.66e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
NEGHOLOK_00954	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
NEGHOLOK_00955	1.03e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
NEGHOLOK_00956	1.14e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
NEGHOLOK_00957	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
NEGHOLOK_00958	4.01e-160	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
NEGHOLOK_00959	7.03e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
NEGHOLOK_00962	6.75e-245	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
NEGHOLOK_00963	2.94e-131	-	-	-	-	-	-	-	-
NEGHOLOK_00964	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
NEGHOLOK_00965	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
NEGHOLOK_00966	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
NEGHOLOK_00969	4.45e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
NEGHOLOK_00970	2.72e-261	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
NEGHOLOK_00971	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
NEGHOLOK_00972	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
NEGHOLOK_00973	1.22e-143	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NEGHOLOK_00974	1.62e-256	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
NEGHOLOK_00975	1.87e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEGHOLOK_00977	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
NEGHOLOK_00979	1.11e-180	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NEGHOLOK_00980	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
NEGHOLOK_00982	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NEGHOLOK_00983	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NEGHOLOK_00985	2.34e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NEGHOLOK_00986	4.75e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
NEGHOLOK_00987	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
NEGHOLOK_00988	2.15e-140	-	-	-	Q	-	-	-	PA14
NEGHOLOK_00991	1.33e-71	-	-	-	-	-	-	-	-
NEGHOLOK_00992	2.83e-93	-	-	-	-	-	-	-	-
NEGHOLOK_00993	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
NEGHOLOK_00994	8.23e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
NEGHOLOK_00996	4.32e-173	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
NEGHOLOK_00997	7.35e-119	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
NEGHOLOK_00998	1.06e-47	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NEGHOLOK_00999	2.41e-99	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NEGHOLOK_01000	9.03e-270	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NEGHOLOK_01001	2e-148	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
NEGHOLOK_01002	2.45e-245	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEGHOLOK_01003	7.87e-150	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
NEGHOLOK_01004	1.64e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NEGHOLOK_01005	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
NEGHOLOK_01006	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01007	2.65e-196	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NEGHOLOK_01008	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
NEGHOLOK_01009	1.53e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NEGHOLOK_01010	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
NEGHOLOK_01011	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
NEGHOLOK_01012	1.12e-248	-	-	-	M	-	-	-	HlyD family secretion protein
NEGHOLOK_01013	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
NEGHOLOK_01014	1.82e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
NEGHOLOK_01016	6.48e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NEGHOLOK_01017	7.56e-246	-	-	-	S	-	-	-	Imelysin
NEGHOLOK_01018	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
NEGHOLOK_01019	2.43e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
NEGHOLOK_01020	4.39e-219	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
NEGHOLOK_01021	2.03e-227	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
NEGHOLOK_01022	1.06e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEGHOLOK_01023	2.42e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
NEGHOLOK_01024	2.69e-185	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
NEGHOLOK_01025	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
NEGHOLOK_01026	2.52e-237	-	-	-	S	-	-	-	Acyltransferase family
NEGHOLOK_01027	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
NEGHOLOK_01028	4.58e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
NEGHOLOK_01029	4.64e-52	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
NEGHOLOK_01030	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
NEGHOLOK_01031	1.56e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
NEGHOLOK_01032	1.1e-228	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NEGHOLOK_01033	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
NEGHOLOK_01034	1.75e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
NEGHOLOK_01035	2.1e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGHOLOK_01036	8.55e-275	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NEGHOLOK_01040	9.16e-208	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
NEGHOLOK_01041	2.71e-269	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
NEGHOLOK_01043	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_01044	5.27e-170	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
NEGHOLOK_01045	2.43e-201	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
NEGHOLOK_01047	2.38e-99	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
NEGHOLOK_01049	1.25e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEGHOLOK_01050	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEGHOLOK_01051	4.73e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
NEGHOLOK_01052	2.29e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEGHOLOK_01053	1.28e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
NEGHOLOK_01056	2.05e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
NEGHOLOK_01057	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NEGHOLOK_01058	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEGHOLOK_01059	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
NEGHOLOK_01060	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
NEGHOLOK_01061	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
NEGHOLOK_01062	4.51e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEGHOLOK_01063	0.0	-	-	-	J	-	-	-	Beta-Casp domain
NEGHOLOK_01064	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NEGHOLOK_01065	1.05e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
NEGHOLOK_01066	4.25e-306	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
NEGHOLOK_01067	1.6e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NEGHOLOK_01068	1.68e-61	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGHOLOK_01069	0.0	-	-	-	C	-	-	-	Cytochrome c
NEGHOLOK_01070	1.57e-298	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
NEGHOLOK_01071	3.17e-157	-	-	-	C	-	-	-	Cytochrome c
NEGHOLOK_01073	9.16e-312	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
NEGHOLOK_01074	1.22e-249	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
NEGHOLOK_01075	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
NEGHOLOK_01076	1.25e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
NEGHOLOK_01077	1.22e-292	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
NEGHOLOK_01078	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEGHOLOK_01079	1.28e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
NEGHOLOK_01080	2.29e-136	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NEGHOLOK_01081	5.53e-285	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
NEGHOLOK_01082	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NEGHOLOK_01083	8.95e-316	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
NEGHOLOK_01084	5.77e-145	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
NEGHOLOK_01085	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
NEGHOLOK_01086	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
NEGHOLOK_01087	1.65e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_01088	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
NEGHOLOK_01089	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEGHOLOK_01090	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEGHOLOK_01091	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NEGHOLOK_01092	1.82e-229	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NEGHOLOK_01093	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NEGHOLOK_01094	1.27e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEGHOLOK_01096	2.57e-120	-	-	-	L	-	-	-	Protein of unknown function DUF262
NEGHOLOK_01097	1.07e-208	-	-	-	EG	-	-	-	EamA-like transporter family
NEGHOLOK_01098	1.81e-282	-	-	-	Q	-	-	-	Multicopper oxidase
NEGHOLOK_01099	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
NEGHOLOK_01100	7.68e-234	-	-	-	O	-	-	-	Parallel beta-helix repeats
NEGHOLOK_01101	1e-219	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NEGHOLOK_01103	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
NEGHOLOK_01104	1.08e-220	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
NEGHOLOK_01105	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
NEGHOLOK_01106	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NEGHOLOK_01107	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
NEGHOLOK_01108	2.34e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
NEGHOLOK_01109	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
NEGHOLOK_01110	1.59e-121	-	-	-	-	-	-	-	-
NEGHOLOK_01111	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEGHOLOK_01112	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NEGHOLOK_01114	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NEGHOLOK_01115	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
NEGHOLOK_01119	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEGHOLOK_01120	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
NEGHOLOK_01121	6.39e-80	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEGHOLOK_01122	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
NEGHOLOK_01125	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
NEGHOLOK_01126	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NEGHOLOK_01127	5.31e-212	MA20_36650	-	-	EG	-	-	-	spore germination
NEGHOLOK_01128	1.52e-191	dpnC	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Dam-replacing family
NEGHOLOK_01129	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
NEGHOLOK_01130	3.91e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
NEGHOLOK_01132	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
NEGHOLOK_01135	5.98e-212	-	-	-	-	-	-	-	-
NEGHOLOK_01136	9.76e-153	-	-	-	O	-	-	-	Glycoprotease family
NEGHOLOK_01137	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
NEGHOLOK_01138	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEGHOLOK_01139	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
NEGHOLOK_01140	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEGHOLOK_01141	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
NEGHOLOK_01142	3.51e-136	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NEGHOLOK_01143	1.26e-214	-	-	-	-	-	-	-	-
NEGHOLOK_01144	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
NEGHOLOK_01145	1.71e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NEGHOLOK_01146	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
NEGHOLOK_01147	1.34e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NEGHOLOK_01148	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
NEGHOLOK_01149	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
NEGHOLOK_01150	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NEGHOLOK_01151	1.04e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEGHOLOK_01152	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
NEGHOLOK_01153	1.57e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NEGHOLOK_01154	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NEGHOLOK_01155	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
NEGHOLOK_01156	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
NEGHOLOK_01157	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
NEGHOLOK_01158	9.28e-170	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
NEGHOLOK_01159	3.98e-190	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
NEGHOLOK_01160	2.37e-291	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NEGHOLOK_01161	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
NEGHOLOK_01162	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
NEGHOLOK_01163	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
NEGHOLOK_01164	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
NEGHOLOK_01165	7.43e-107	-	-	-	-	-	-	-	-
NEGHOLOK_01167	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
NEGHOLOK_01168	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01169	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
NEGHOLOK_01170	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
NEGHOLOK_01171	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01172	6.53e-158	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
NEGHOLOK_01173	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01174	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NEGHOLOK_01175	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
NEGHOLOK_01176	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
NEGHOLOK_01177	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
NEGHOLOK_01178	3.6e-306	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01180	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
NEGHOLOK_01181	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
NEGHOLOK_01182	4.37e-141	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
NEGHOLOK_01183	5.71e-202	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
NEGHOLOK_01184	0.0	pmp21	-	-	T	-	-	-	pathogenesis
NEGHOLOK_01185	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NEGHOLOK_01187	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
NEGHOLOK_01188	0.0	-	-	-	-	ko:K07403	-	ko00000	-
NEGHOLOK_01189	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEGHOLOK_01190	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEGHOLOK_01191	3.72e-187	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
NEGHOLOK_01194	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEGHOLOK_01195	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
NEGHOLOK_01196	8.06e-216	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
NEGHOLOK_01197	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
NEGHOLOK_01198	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
NEGHOLOK_01199	4.81e-311	-	-	-	O	-	-	-	peroxiredoxin activity
NEGHOLOK_01200	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
NEGHOLOK_01201	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
NEGHOLOK_01202	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
NEGHOLOK_01203	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01204	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
NEGHOLOK_01205	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEGHOLOK_01206	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NEGHOLOK_01207	1.84e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NEGHOLOK_01208	1.2e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NEGHOLOK_01209	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEGHOLOK_01210	6.25e-288	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
NEGHOLOK_01212	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
NEGHOLOK_01213	7.83e-140	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NEGHOLOK_01214	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NEGHOLOK_01217	3.25e-223	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
NEGHOLOK_01218	3.85e-152	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
NEGHOLOK_01219	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
NEGHOLOK_01220	0.0	-	-	-	P	-	-	-	Sulfatase
NEGHOLOK_01222	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
NEGHOLOK_01223	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
NEGHOLOK_01224	8.87e-269	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_01225	3.64e-183	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NEGHOLOK_01226	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
NEGHOLOK_01227	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
NEGHOLOK_01228	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
NEGHOLOK_01229	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_01231	3.87e-301	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
NEGHOLOK_01232	3.67e-216	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
NEGHOLOK_01233	2.18e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
NEGHOLOK_01236	4.46e-127	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
NEGHOLOK_01237	1.65e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
NEGHOLOK_01238	1.62e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NEGHOLOK_01239	4.02e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NEGHOLOK_01240	7.18e-234	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NEGHOLOK_01241	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NEGHOLOK_01242	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
NEGHOLOK_01243	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NEGHOLOK_01244	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
NEGHOLOK_01245	6.65e-160	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NEGHOLOK_01246	2.31e-313	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NEGHOLOK_01247	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEGHOLOK_01248	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
NEGHOLOK_01249	8.04e-60	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
NEGHOLOK_01250	5.45e-225	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
NEGHOLOK_01251	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
NEGHOLOK_01252	1.21e-244	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
NEGHOLOK_01253	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
NEGHOLOK_01254	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEGHOLOK_01255	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NEGHOLOK_01256	0.0	-	-	-	T	-	-	-	Chase2 domain
NEGHOLOK_01257	2.51e-234	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
NEGHOLOK_01258	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEGHOLOK_01259	1e-91	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEGHOLOK_01261	2.46e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
NEGHOLOK_01262	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01263	5.44e-104	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
NEGHOLOK_01265	2.91e-114	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
NEGHOLOK_01267	3.45e-178	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
NEGHOLOK_01273	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
NEGHOLOK_01275	0.00011	xerA	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules
NEGHOLOK_01278	4.6e-05	-	-	-	-	-	-	-	-
NEGHOLOK_01286	5.98e-66	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NEGHOLOK_01291	5.46e-22	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
NEGHOLOK_01292	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
NEGHOLOK_01293	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
NEGHOLOK_01294	3.26e-226	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NEGHOLOK_01295	2.03e-100	-	-	-	-	-	-	-	-
NEGHOLOK_01296	2.15e-192	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NEGHOLOK_01297	3.84e-180	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
NEGHOLOK_01298	4.49e-125	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
NEGHOLOK_01299	8.21e-246	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
NEGHOLOK_01300	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
NEGHOLOK_01301	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
NEGHOLOK_01302	6e-76	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
NEGHOLOK_01303	1.54e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NEGHOLOK_01304	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
NEGHOLOK_01305	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
NEGHOLOK_01306	2.55e-94	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
NEGHOLOK_01307	6.13e-165	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
NEGHOLOK_01308	2.63e-206	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEGHOLOK_01309	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
NEGHOLOK_01310	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
NEGHOLOK_01311	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
NEGHOLOK_01312	5.86e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
NEGHOLOK_01313	9.9e-121	-	-	-	-	-	-	-	-
NEGHOLOK_01315	1.17e-231	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NEGHOLOK_01316	9.23e-124	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NEGHOLOK_01317	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NEGHOLOK_01318	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
NEGHOLOK_01319	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
NEGHOLOK_01320	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
NEGHOLOK_01327	1.04e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
NEGHOLOK_01328	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEGHOLOK_01329	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
NEGHOLOK_01330	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
NEGHOLOK_01332	2.31e-232	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
NEGHOLOK_01333	3.58e-239	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
NEGHOLOK_01334	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
NEGHOLOK_01335	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
NEGHOLOK_01336	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
NEGHOLOK_01337	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
NEGHOLOK_01338	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
NEGHOLOK_01339	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEGHOLOK_01340	1.65e-244	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEGHOLOK_01341	6.23e-123	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NEGHOLOK_01342	5.75e-98	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
NEGHOLOK_01344	4.09e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
NEGHOLOK_01345	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_01346	2.69e-310	-	-	-	V	-	-	-	MacB-like periplasmic core domain
NEGHOLOK_01347	8.19e-316	-	-	-	MU	-	-	-	Outer membrane efflux protein
NEGHOLOK_01348	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
NEGHOLOK_01349	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEGHOLOK_01350	8.54e-283	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEGHOLOK_01351	1.02e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NEGHOLOK_01352	2.51e-167	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
NEGHOLOK_01353	1.37e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
NEGHOLOK_01354	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
NEGHOLOK_01355	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
NEGHOLOK_01356	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
NEGHOLOK_01358	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
NEGHOLOK_01359	6.45e-268	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
NEGHOLOK_01360	2.11e-89	-	-	-	-	-	-	-	-
NEGHOLOK_01361	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
NEGHOLOK_01362	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
NEGHOLOK_01363	0.0	-	-	-	P	-	-	-	Domain of unknown function
NEGHOLOK_01365	1.13e-111	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NEGHOLOK_01366	6.46e-312	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
NEGHOLOK_01367	1.91e-186	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEGHOLOK_01369	1.83e-74	-	-	-	-	-	-	-	-
NEGHOLOK_01370	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
NEGHOLOK_01372	1.29e-132	-	-	-	S	-	-	-	Glycosyl hydrolase 108
NEGHOLOK_01375	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
NEGHOLOK_01376	5.07e-235	-	-	-	S	-	-	-	Peptidase family M28
NEGHOLOK_01377	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
NEGHOLOK_01378	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
NEGHOLOK_01381	1.11e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
NEGHOLOK_01382	4.56e-273	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
NEGHOLOK_01384	1.01e-84	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
NEGHOLOK_01385	1.87e-212	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NEGHOLOK_01386	1.6e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEGHOLOK_01387	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NEGHOLOK_01388	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NEGHOLOK_01389	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
NEGHOLOK_01390	4.57e-311	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
NEGHOLOK_01391	3.02e-236	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
NEGHOLOK_01394	1.81e-310	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
NEGHOLOK_01395	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEGHOLOK_01396	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
NEGHOLOK_01397	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
NEGHOLOK_01398	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
NEGHOLOK_01399	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
NEGHOLOK_01400	0.0	-	-	-	H	-	-	-	NAD synthase
NEGHOLOK_01401	1.49e-167	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
NEGHOLOK_01402	1.75e-189	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_01403	1.9e-231	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
NEGHOLOK_01404	2.69e-38	-	-	-	T	-	-	-	ribosome binding
NEGHOLOK_01407	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NEGHOLOK_01408	3.71e-260	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NEGHOLOK_01409	3.36e-248	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
NEGHOLOK_01411	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01412	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NEGHOLOK_01413	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEGHOLOK_01414	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
NEGHOLOK_01415	7.07e-249	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NEGHOLOK_01416	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NEGHOLOK_01420	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NEGHOLOK_01421	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
NEGHOLOK_01422	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
NEGHOLOK_01423	4.16e-178	-	-	-	M	-	-	-	NLP P60 protein
NEGHOLOK_01424	1.37e-86	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
NEGHOLOK_01426	8.53e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
NEGHOLOK_01427	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
NEGHOLOK_01428	9.22e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
NEGHOLOK_01429	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
NEGHOLOK_01430	6.94e-298	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
NEGHOLOK_01431	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
NEGHOLOK_01433	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEGHOLOK_01435	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEGHOLOK_01436	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
NEGHOLOK_01437	0.0	-	-	-	M	-	-	-	Transglycosylase
NEGHOLOK_01438	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
NEGHOLOK_01439	3.22e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
NEGHOLOK_01440	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NEGHOLOK_01441	4.08e-215	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NEGHOLOK_01443	5.79e-274	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
NEGHOLOK_01444	2.56e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
NEGHOLOK_01446	5.7e-241	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
NEGHOLOK_01447	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
NEGHOLOK_01448	1.07e-157	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEGHOLOK_01449	2.76e-129	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEGHOLOK_01450	3.55e-257	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
NEGHOLOK_01451	5.92e-231	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
NEGHOLOK_01452	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
NEGHOLOK_01453	9.53e-317	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
NEGHOLOK_01455	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NEGHOLOK_01456	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
NEGHOLOK_01457	1.06e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NEGHOLOK_01458	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
NEGHOLOK_01459	3.57e-283	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
NEGHOLOK_01461	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NEGHOLOK_01462	3.66e-229	-	-	-	C	-	-	-	Nitroreductase family
NEGHOLOK_01463	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
NEGHOLOK_01464	8.91e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01465	1.55e-39	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NEGHOLOK_01466	6.44e-239	-	-	-	M	-	-	-	Glycosyl transferase, family 2
NEGHOLOK_01467	1.42e-209	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
NEGHOLOK_01468	5.38e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
NEGHOLOK_01469	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01470	3.29e-279	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEGHOLOK_01471	5.46e-281	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NEGHOLOK_01472	8.31e-253	-	-	-	M	-	-	-	Glycosyl transferases group 1
NEGHOLOK_01473	1.52e-201	-	-	-	S	-	-	-	Glycosyl transferase family 11
NEGHOLOK_01474	3.73e-263	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
NEGHOLOK_01475	3.46e-241	-	-	-	-	-	-	-	-
NEGHOLOK_01476	6.05e-295	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
NEGHOLOK_01477	2.84e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEGHOLOK_01478	1.47e-292	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEGHOLOK_01479	1.2e-189	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
NEGHOLOK_01480	6.88e-176	-	-	-	M	-	-	-	Bacterial sugar transferase
NEGHOLOK_01481	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
NEGHOLOK_01482	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
NEGHOLOK_01483	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
NEGHOLOK_01498	1.4e-09	-	-	-	S	-	-	-	Mu-like prophage I protein
NEGHOLOK_01501	1.38e-76	-	-	-	S	-	-	-	Mu-like prophage FluMu protein gp28
NEGHOLOK_01505	1.98e-12	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NEGHOLOK_01521	0.000705	-	-	-	K	-	-	-	sequence-specific DNA binding
NEGHOLOK_01522	8.31e-62	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NEGHOLOK_01523	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
NEGHOLOK_01525	7.6e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEGHOLOK_01526	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
NEGHOLOK_01527	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
NEGHOLOK_01529	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
NEGHOLOK_01530	1.17e-44	-	-	-	S	-	-	-	R3H domain
NEGHOLOK_01532	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
NEGHOLOK_01533	1.79e-282	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NEGHOLOK_01536	1.71e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NEGHOLOK_01537	9.88e-145	-	-	-	-	-	-	-	-
NEGHOLOK_01539	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
NEGHOLOK_01541	1.56e-182	-	-	-	-	-	-	-	-
NEGHOLOK_01543	1.46e-72	-	-	-	S	-	-	-	PFAM KAP P-loop domain protein
NEGHOLOK_01551	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01552	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEGHOLOK_01553	1.14e-166	-	-	-	-	-	-	-	-
NEGHOLOK_01554	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
NEGHOLOK_01555	4.14e-279	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
NEGHOLOK_01557	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
NEGHOLOK_01558	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
NEGHOLOK_01559	2.51e-06	-	-	-	-	-	-	-	-
NEGHOLOK_01560	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NEGHOLOK_01561	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
NEGHOLOK_01564	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
NEGHOLOK_01566	1.87e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
NEGHOLOK_01567	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
NEGHOLOK_01568	9.41e-233	-	-	-	CO	-	-	-	Redoxin
NEGHOLOK_01569	4.73e-85	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
NEGHOLOK_01570	7.41e-177	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
NEGHOLOK_01572	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEGHOLOK_01573	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEGHOLOK_01574	3.58e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
NEGHOLOK_01576	2.82e-42	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
NEGHOLOK_01579	1.05e-19	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
NEGHOLOK_01596	5.83e-30	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
NEGHOLOK_01597	1.09e-12	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NEGHOLOK_01599	0.000452	-	-	-	S	-	-	-	Putative phage abortive infection protein
NEGHOLOK_01609	9.34e-11	-	-	-	-	-	-	-	-
NEGHOLOK_01611	8.13e-06	-	-	-	L	ko:K07505	-	ko00000	Primase C terminal 2 (PriCT-2)
NEGHOLOK_01612	2.73e-22	traC	-	-	P	-	-	-	DNA integration
NEGHOLOK_01613	4.06e-41	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NEGHOLOK_01615	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
NEGHOLOK_01616	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEGHOLOK_01617	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NEGHOLOK_01618	2.49e-183	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEGHOLOK_01619	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
NEGHOLOK_01620	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
NEGHOLOK_01621	1.57e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
NEGHOLOK_01622	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NEGHOLOK_01623	3.98e-277	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
NEGHOLOK_01624	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NEGHOLOK_01625	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEGHOLOK_01626	1.03e-144	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
NEGHOLOK_01628	5.78e-287	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
NEGHOLOK_01630	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
NEGHOLOK_01631	5.73e-288	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NEGHOLOK_01632	1.49e-225	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
NEGHOLOK_01633	2.23e-272	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
NEGHOLOK_01634	8.94e-317	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
NEGHOLOK_01635	9.46e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEGHOLOK_01636	4.17e-190	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
NEGHOLOK_01638	8.84e-140	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
NEGHOLOK_01639	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01640	1.38e-294	-	-	-	-	-	-	-	-
NEGHOLOK_01641	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
NEGHOLOK_01643	1.01e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
NEGHOLOK_01644	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NEGHOLOK_01645	2.27e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
NEGHOLOK_01647	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
NEGHOLOK_01648	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
NEGHOLOK_01651	3.12e-202	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NEGHOLOK_01652	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NEGHOLOK_01653	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
NEGHOLOK_01654	1.43e-220	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
NEGHOLOK_01655	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
NEGHOLOK_01656	7.09e-309	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
NEGHOLOK_01658	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEGHOLOK_01659	1.65e-213	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEGHOLOK_01660	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEGHOLOK_01661	1.25e-199	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEGHOLOK_01665	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
NEGHOLOK_01666	0.0	-	-	-	V	-	-	-	MatE
NEGHOLOK_01668	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGHOLOK_01670	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEGHOLOK_01671	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEGHOLOK_01672	4.97e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEGHOLOK_01673	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEGHOLOK_01674	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
NEGHOLOK_01675	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
NEGHOLOK_01677	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEGHOLOK_01679	8.34e-255	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEGHOLOK_01680	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEGHOLOK_01681	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEGHOLOK_01682	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEGHOLOK_01683	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
NEGHOLOK_01684	5.9e-156	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
NEGHOLOK_01685	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NEGHOLOK_01686	1.38e-168	-	-	-	CO	-	-	-	Protein conserved in bacteria
NEGHOLOK_01688	1.46e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEGHOLOK_01689	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
NEGHOLOK_01690	1.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEGHOLOK_01691	3.69e-296	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
NEGHOLOK_01693	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
NEGHOLOK_01694	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
NEGHOLOK_01697	1.66e-215	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
NEGHOLOK_01698	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEGHOLOK_01699	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NEGHOLOK_01700	1.81e-251	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEGHOLOK_01701	1.87e-248	-	-	-	-	-	-	-	-
NEGHOLOK_01702	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NEGHOLOK_01703	1.44e-225	-	-	-	-	-	-	-	-
NEGHOLOK_01704	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
NEGHOLOK_01705	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
NEGHOLOK_01707	1.45e-299	-	-	-	M	-	-	-	Glycosyl transferases group 1
NEGHOLOK_01708	1.62e-256	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
NEGHOLOK_01709	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
NEGHOLOK_01710	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
NEGHOLOK_01711	4.56e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
NEGHOLOK_01712	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
NEGHOLOK_01713	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
NEGHOLOK_01715	1.63e-302	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
NEGHOLOK_01718	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
NEGHOLOK_01719	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
NEGHOLOK_01720	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
NEGHOLOK_01721	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
NEGHOLOK_01722	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NEGHOLOK_01723	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEGHOLOK_01724	1.65e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEGHOLOK_01725	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
NEGHOLOK_01726	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEGHOLOK_01727	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEGHOLOK_01728	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
NEGHOLOK_01729	2.27e-245	-	-	-	-	-	-	-	-
NEGHOLOK_01730	8.68e-208	-	-	-	-	-	-	-	-
NEGHOLOK_01731	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
NEGHOLOK_01732	2.8e-169	-	-	-	-	-	-	-	-
NEGHOLOK_01733	9.39e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
NEGHOLOK_01734	1.3e-263	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEGHOLOK_01735	2.82e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
NEGHOLOK_01736	8.33e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
NEGHOLOK_01737	2.25e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NEGHOLOK_01738	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
NEGHOLOK_01739	8.6e-291	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NEGHOLOK_01740	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NEGHOLOK_01741	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
NEGHOLOK_01743	0.0	-	-	-	T	-	-	-	pathogenesis
NEGHOLOK_01744	4.71e-267	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NEGHOLOK_01745	6.59e-205	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
NEGHOLOK_01746	6.68e-286	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
NEGHOLOK_01747	0.0	-	-	-	M	-	-	-	Sulfatase
NEGHOLOK_01748	3.09e-290	-	-	-	-	-	-	-	-
NEGHOLOK_01749	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NEGHOLOK_01750	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
NEGHOLOK_01751	6.39e-119	-	-	-	T	-	-	-	STAS domain
NEGHOLOK_01752	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
NEGHOLOK_01753	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
NEGHOLOK_01754	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
NEGHOLOK_01755	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
NEGHOLOK_01756	7.2e-103	-	-	-	-	-	-	-	-
NEGHOLOK_01757	9.86e-54	-	-	-	-	-	-	-	-
NEGHOLOK_01758	1.83e-120	-	-	-	-	-	-	-	-
NEGHOLOK_01759	3.53e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
NEGHOLOK_01760	0.0	-	-	-	P	-	-	-	Cation transport protein
NEGHOLOK_01763	5.37e-148	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NEGHOLOK_01769	3.72e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
NEGHOLOK_01771	0.0	-	-	-	M	-	-	-	pathogenesis
NEGHOLOK_01772	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NEGHOLOK_01774	4.07e-97	-	-	-	S	-	-	-	peptidase
NEGHOLOK_01775	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
NEGHOLOK_01776	2.24e-101	-	-	-	S	-	-	-	peptidase
NEGHOLOK_01777	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
NEGHOLOK_01778	1.38e-90	-	-	-	-	-	-	-	-
NEGHOLOK_01779	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
NEGHOLOK_01783	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
NEGHOLOK_01784	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
NEGHOLOK_01785	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
NEGHOLOK_01787	2.51e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEGHOLOK_01789	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
NEGHOLOK_01790	1.17e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
NEGHOLOK_01791	4.75e-215	-	-	-	K	-	-	-	LysR substrate binding domain
NEGHOLOK_01792	3.03e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NEGHOLOK_01794	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
NEGHOLOK_01795	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
NEGHOLOK_01796	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEGHOLOK_01798	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
NEGHOLOK_01799	1.12e-288	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
NEGHOLOK_01801	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NEGHOLOK_01802	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
NEGHOLOK_01803	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
NEGHOLOK_01804	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
NEGHOLOK_01805	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEGHOLOK_01806	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
NEGHOLOK_01807	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEGHOLOK_01808	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEGHOLOK_01809	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEGHOLOK_01810	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEGHOLOK_01811	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEGHOLOK_01812	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
NEGHOLOK_01814	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEGHOLOK_01815	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEGHOLOK_01816	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
NEGHOLOK_01817	2e-264	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NEGHOLOK_01818	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NEGHOLOK_01819	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
NEGHOLOK_01820	1.19e-280	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
NEGHOLOK_01822	3.93e-272	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
NEGHOLOK_01823	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
NEGHOLOK_01824	3.16e-259	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NEGHOLOK_01825	2.27e-290	-	-	-	-	-	-	-	-
NEGHOLOK_01826	8.81e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
NEGHOLOK_01827	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NEGHOLOK_01828	3.78e-228	-	-	-	C	-	-	-	e3 binding domain
NEGHOLOK_01829	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEGHOLOK_01830	8.17e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEGHOLOK_01831	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
NEGHOLOK_01832	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
NEGHOLOK_01833	8.65e-155	-	-	-	-	-	-	-	-
NEGHOLOK_01834	1.28e-15	-	-	-	-	-	-	-	-
NEGHOLOK_01835	0.0	-	-	-	P	-	-	-	PA14 domain
NEGHOLOK_01836	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEGHOLOK_01837	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEGHOLOK_01838	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
NEGHOLOK_01839	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
NEGHOLOK_01840	2.86e-143	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEGHOLOK_01841	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
NEGHOLOK_01842	3.3e-203	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
NEGHOLOK_01843	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
NEGHOLOK_01844	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
NEGHOLOK_01846	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_01847	3.54e-185	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEGHOLOK_01848	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
NEGHOLOK_01849	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
NEGHOLOK_01850	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
NEGHOLOK_01851	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
NEGHOLOK_01853	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
NEGHOLOK_01854	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEGHOLOK_01855	1.18e-273	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
NEGHOLOK_01856	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
NEGHOLOK_01857	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
NEGHOLOK_01858	3.5e-132	-	-	-	-	-	-	-	-
NEGHOLOK_01859	1.67e-174	-	-	-	S	-	-	-	Lysin motif
NEGHOLOK_01860	5.31e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEGHOLOK_01862	7.38e-17	-	-	-	M	-	-	-	self proteolysis
NEGHOLOK_01864	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NEGHOLOK_01865	9.19e-229	-	-	-	O	-	-	-	Trypsin-like peptidase domain
NEGHOLOK_01866	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
NEGHOLOK_01867	1.21e-285	-	-	-	S	ko:K09760	-	ko00000	RmuC family
NEGHOLOK_01868	5.69e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NEGHOLOK_01869	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NEGHOLOK_01870	7.56e-208	-	-	-	S	-	-	-	RDD family
NEGHOLOK_01871	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
NEGHOLOK_01872	1.38e-209	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NEGHOLOK_01873	2.27e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
NEGHOLOK_01874	4.81e-58	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NEGHOLOK_01875	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NEGHOLOK_01876	1.55e-258	-	-	-	S	-	-	-	Peptidase family M28
NEGHOLOK_01877	3.92e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEGHOLOK_01878	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEGHOLOK_01879	1.24e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
NEGHOLOK_01880	6.88e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
NEGHOLOK_01881	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
NEGHOLOK_01882	1.9e-298	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEGHOLOK_01883	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NEGHOLOK_01884	0.000231	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
NEGHOLOK_01886	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEGHOLOK_01887	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_01888	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
NEGHOLOK_01889	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
NEGHOLOK_01891	6.88e-55	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
NEGHOLOK_01892	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
NEGHOLOK_01893	2.72e-191	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NEGHOLOK_01894	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
NEGHOLOK_01896	2.24e-204	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NEGHOLOK_01897	7.56e-271	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
NEGHOLOK_01898	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
NEGHOLOK_01899	4.51e-182	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
NEGHOLOK_01901	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGHOLOK_01902	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
NEGHOLOK_01903	0.000225	-	-	-	-	-	-	-	-
NEGHOLOK_01904	0.0	-	-	-	G	-	-	-	alpha-galactosidase
NEGHOLOK_01906	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NEGHOLOK_01907	1.53e-284	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEGHOLOK_01908	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEGHOLOK_01909	9.04e-317	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
NEGHOLOK_01911	6.08e-178	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NEGHOLOK_01913	7.63e-166	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
NEGHOLOK_01916	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
NEGHOLOK_01919	3.92e-115	-	-	-	-	-	-	-	-
NEGHOLOK_01920	4.46e-182	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NEGHOLOK_01922	5.46e-161	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEGHOLOK_01923	5.91e-261	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NEGHOLOK_01924	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
NEGHOLOK_01925	8.34e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
NEGHOLOK_01926	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
NEGHOLOK_01927	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
NEGHOLOK_01928	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NEGHOLOK_01929	8.75e-240	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
NEGHOLOK_01931	2.75e-185	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NEGHOLOK_01932	2.05e-28	-	-	-	-	-	-	-	-
NEGHOLOK_01933	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
NEGHOLOK_01934	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEGHOLOK_01935	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NEGHOLOK_01936	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
NEGHOLOK_01937	8.55e-135	-	-	-	C	-	-	-	Nitroreductase family
NEGHOLOK_01938	1.75e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
NEGHOLOK_01943	8.51e-210	-	-	-	M	-	-	-	Peptidase family M23
NEGHOLOK_01944	5.87e-228	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NEGHOLOK_01945	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NEGHOLOK_01946	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NEGHOLOK_01947	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
NEGHOLOK_01948	1.25e-204	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NEGHOLOK_01950	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
NEGHOLOK_01952	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
NEGHOLOK_01953	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
NEGHOLOK_01955	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
NEGHOLOK_01956	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
NEGHOLOK_01957	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
NEGHOLOK_01958	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEGHOLOK_01960	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
NEGHOLOK_01962	1.39e-173	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
NEGHOLOK_01963	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEGHOLOK_01964	1.07e-30	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEGHOLOK_01965	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEGHOLOK_01966	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
NEGHOLOK_01967	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
NEGHOLOK_01968	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEGHOLOK_01969	6.34e-183	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NEGHOLOK_01970	1.08e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
NEGHOLOK_01971	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_01972	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
NEGHOLOK_01973	8.31e-186	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NEGHOLOK_01974	1.12e-116	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEGHOLOK_01975	5.27e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
NEGHOLOK_01976	1.14e-227	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
NEGHOLOK_01977	1.11e-236	-	-	-	-	-	-	-	-
NEGHOLOK_01978	4.15e-296	-	-	-	C	-	-	-	Na+/H+ antiporter family
NEGHOLOK_01979	2.53e-266	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
NEGHOLOK_01980	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NEGHOLOK_01981	2.56e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
NEGHOLOK_01982	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NEGHOLOK_01983	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NEGHOLOK_01984	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
NEGHOLOK_01985	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
NEGHOLOK_01986	8.98e-59	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
NEGHOLOK_01987	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
NEGHOLOK_01988	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
NEGHOLOK_01989	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NEGHOLOK_01990	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NEGHOLOK_01991	0.0	-	-	-	G	-	-	-	Trehalase
NEGHOLOK_01992	2.45e-211	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NEGHOLOK_01993	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
NEGHOLOK_01994	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
NEGHOLOK_01995	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
NEGHOLOK_01996	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEGHOLOK_01998	5.5e-176	-	-	-	-	-	-	-	-
NEGHOLOK_01999	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
NEGHOLOK_02000	1.02e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
NEGHOLOK_02001	1.96e-224	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
NEGHOLOK_02002	1.33e-133	panZ	-	-	K	-	-	-	-acetyltransferase
NEGHOLOK_02007	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NEGHOLOK_02008	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
NEGHOLOK_02009	2.54e-208	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NEGHOLOK_02010	8.59e-273	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
NEGHOLOK_02011	5.35e-139	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEGHOLOK_02012	1.05e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
NEGHOLOK_02021	2.69e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
NEGHOLOK_02023	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NEGHOLOK_02024	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
NEGHOLOK_02025	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
NEGHOLOK_02027	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
NEGHOLOK_02028	1.64e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
NEGHOLOK_02029	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
NEGHOLOK_02031	5.04e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
NEGHOLOK_02032	1.62e-172	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NEGHOLOK_02033	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
NEGHOLOK_02034	7.49e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
NEGHOLOK_02035	1.05e-226	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NEGHOLOK_02036	9.16e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NEGHOLOK_02037	2.84e-18	-	-	-	S	-	-	-	Lipocalin-like
NEGHOLOK_02039	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
NEGHOLOK_02040	1.99e-194	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
NEGHOLOK_02041	4.82e-179	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
NEGHOLOK_02042	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
NEGHOLOK_02044	1.42e-209	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
NEGHOLOK_02045	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
NEGHOLOK_02046	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEGHOLOK_02047	2.41e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NEGHOLOK_02048	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
NEGHOLOK_02049	3.85e-235	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NEGHOLOK_02050	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NEGHOLOK_02051	1.04e-49	-	-	-	-	-	-	-	-
NEGHOLOK_02052	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
NEGHOLOK_02053	1.84e-221	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEGHOLOK_02054	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
NEGHOLOK_02055	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEGHOLOK_02056	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
NEGHOLOK_02058	0.0	-	-	-	P	-	-	-	Sulfatase
NEGHOLOK_02060	9.64e-153	-	-	-	K	-	-	-	Transcriptional regulator
NEGHOLOK_02061	2.92e-189	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_02062	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEGHOLOK_02063	1.03e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
NEGHOLOK_02064	2.29e-208	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
NEGHOLOK_02065	3.48e-203	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
NEGHOLOK_02067	4.01e-240	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NEGHOLOK_02069	4.24e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NEGHOLOK_02070	2.12e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NEGHOLOK_02071	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_02072	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NEGHOLOK_02073	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
NEGHOLOK_02074	1.58e-205	-	-	-	S	-	-	-	Protein of unknown function DUF58
NEGHOLOK_02075	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
NEGHOLOK_02076	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
NEGHOLOK_02077	2.53e-293	-	-	-	-	-	-	-	-
NEGHOLOK_02078	4.05e-259	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
NEGHOLOK_02079	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NEGHOLOK_02080	2.81e-280	-	-	-	C	-	-	-	Aldo/keto reductase family
NEGHOLOK_02081	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NEGHOLOK_02082	3.34e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
NEGHOLOK_02083	4.85e-195	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NEGHOLOK_02085	2.06e-232	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
NEGHOLOK_02086	3.88e-263	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
NEGHOLOK_02088	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NEGHOLOK_02089	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NEGHOLOK_02090	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NEGHOLOK_02091	4.41e-13	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NEGHOLOK_02094	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
NEGHOLOK_02095	1.17e-241	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
NEGHOLOK_02096	4.49e-191	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NEGHOLOK_02097	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NEGHOLOK_02098	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
NEGHOLOK_02099	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
NEGHOLOK_02100	3.32e-206	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
NEGHOLOK_02103	8.73e-87	-	-	-	-	-	-	-	-
NEGHOLOK_02104	5.6e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
NEGHOLOK_02105	8.39e-191	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
NEGHOLOK_02106	1.06e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
NEGHOLOK_02107	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
NEGHOLOK_02108	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NEGHOLOK_02109	2.85e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
NEGHOLOK_02110	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
NEGHOLOK_02111	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
NEGHOLOK_02112	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NEGHOLOK_02113	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
NEGHOLOK_02114	8.34e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
NEGHOLOK_02115	4.93e-286	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NEGHOLOK_02116	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_02117	2.54e-267	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
NEGHOLOK_02119	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
NEGHOLOK_02121	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
NEGHOLOK_02122	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
NEGHOLOK_02123	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
NEGHOLOK_02124	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
NEGHOLOK_02125	1.52e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
NEGHOLOK_02126	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
NEGHOLOK_02127	0.0	-	-	-	T	-	-	-	Histidine kinase
NEGHOLOK_02128	1.33e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
NEGHOLOK_02129	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NEGHOLOK_02130	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
NEGHOLOK_02131	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
NEGHOLOK_02132	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_02135	6.96e-305	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
NEGHOLOK_02136	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEGHOLOK_02137	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NEGHOLOK_02138	3.29e-258	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NEGHOLOK_02139	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NEGHOLOK_02140	4.2e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEGHOLOK_02141	2.46e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEGHOLOK_02142	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_02143	1.24e-163	-	-	-	S	-	-	-	SWIM zinc finger
NEGHOLOK_02144	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
NEGHOLOK_02145	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
NEGHOLOK_02146	7.2e-125	-	-	-	-	-	-	-	-
NEGHOLOK_02147	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEGHOLOK_02148	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
NEGHOLOK_02149	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NEGHOLOK_02150	0.0	-	-	-	S	-	-	-	Oxygen tolerance
NEGHOLOK_02151	1.36e-204	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
NEGHOLOK_02152	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
NEGHOLOK_02153	8.72e-155	-	-	-	S	-	-	-	DUF218 domain
NEGHOLOK_02154	9.2e-208	-	-	-	S	-	-	-	CAAX protease self-immunity
NEGHOLOK_02155	3.2e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
NEGHOLOK_02156	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
NEGHOLOK_02157	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NEGHOLOK_02158	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
NEGHOLOK_02159	7.47e-203	-	-	-	-	-	-	-	-
NEGHOLOK_02160	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NEGHOLOK_02161	3.67e-193	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEGHOLOK_02162	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
NEGHOLOK_02163	1.02e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
NEGHOLOK_02164	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
NEGHOLOK_02165	3.48e-140	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
NEGHOLOK_02166	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEGHOLOK_02167	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
NEGHOLOK_02168	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
NEGHOLOK_02169	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NEGHOLOK_02170	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEGHOLOK_02171	0.0	-	-	-	P	-	-	-	Sulfatase
NEGHOLOK_02172	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEGHOLOK_02173	5.06e-94	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
NEGHOLOK_02175	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
NEGHOLOK_02176	1.97e-260	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
NEGHOLOK_02177	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
NEGHOLOK_02178	2.13e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
NEGHOLOK_02179	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NEGHOLOK_02180	2.54e-226	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
NEGHOLOK_02181	2.33e-130	-	-	-	S	-	-	-	protein trimerization
NEGHOLOK_02183	1.84e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
NEGHOLOK_02184	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
NEGHOLOK_02185	1.67e-123	-	-	-	-	-	-	-	-
NEGHOLOK_02186	3.09e-61	-	-	-	J	-	-	-	RF-1 domain
NEGHOLOK_02187	5.73e-120	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEGHOLOK_02188	1.28e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
NEGHOLOK_02189	4.43e-291	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NEGHOLOK_02190	9.6e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NEGHOLOK_02191	6.63e-144	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_02192	2.92e-163	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NEGHOLOK_02193	8.71e-301	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NEGHOLOK_02194	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
NEGHOLOK_02196	3.29e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEGHOLOK_02197	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEGHOLOK_02199	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
NEGHOLOK_02201	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NEGHOLOK_02202	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NEGHOLOK_02203	5.99e-231	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
NEGHOLOK_02204	5.27e-184	-	-	-	I	-	-	-	Acyl-ACP thioesterase
NEGHOLOK_02205	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
NEGHOLOK_02206	3.05e-170	-	-	-	S	ko:K06911	-	ko00000	Pirin
NEGHOLOK_02208	2.4e-172	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
NEGHOLOK_02211	1.42e-215	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEGHOLOK_02212	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
NEGHOLOK_02213	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
NEGHOLOK_02214	0.0	-	-	-	-	-	-	-	-
NEGHOLOK_02215	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
NEGHOLOK_02216	2.51e-215	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NEGHOLOK_02217	5.51e-240	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
NEGHOLOK_02218	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NEGHOLOK_02220	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
NEGHOLOK_02221	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NEGHOLOK_02222	2.54e-83	-	-	-	G	-	-	-	single-species biofilm formation
NEGHOLOK_02223	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NEGHOLOK_02224	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
NEGHOLOK_02225	1.11e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
NEGHOLOK_02226	8.08e-100	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NEGHOLOK_02227	1.66e-127	-	-	-	C	-	-	-	FMN binding
NEGHOLOK_02228	3.6e-265	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
NEGHOLOK_02229	1.48e-270	-	-	-	C	-	-	-	Aldo/keto reductase family
NEGHOLOK_02230	1.41e-266	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
NEGHOLOK_02231	1.3e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
NEGHOLOK_02232	9.88e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
NEGHOLOK_02233	6.91e-302	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NEGHOLOK_02234	2.29e-141	-	-	-	M	-	-	-	polygalacturonase activity
NEGHOLOK_02236	2.07e-195	-	-	-	KT	-	-	-	Peptidase S24-like
NEGHOLOK_02237	6.03e-292	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NEGHOLOK_02240	3.4e-178	-	-	-	O	-	-	-	Trypsin
NEGHOLOK_02241	5.49e-238	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NEGHOLOK_02242	6.2e-203	-	-	-	-	-	-	-	-
NEGHOLOK_02243	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
NEGHOLOK_02244	1.85e-282	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEGHOLOK_02247	2.63e-10	-	-	-	-	-	-	-	-
NEGHOLOK_02249	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGHOLOK_02250	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEGHOLOK_02251	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NEGHOLOK_02252	4.38e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
NEGHOLOK_02253	8.06e-134	-	-	-	-	-	-	-	-
NEGHOLOK_02254	1.33e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
NEGHOLOK_02260	3.45e-153	-	-	-	-	-	-	-	-
NEGHOLOK_02262	1.31e-38	-	-	-	-	-	-	-	-
NEGHOLOK_02268	1.78e-34	-	-	-	-	-	-	-	-
NEGHOLOK_02270	7.53e-96	-	-	-	L	-	-	-	Transposase and inactivated derivatives
NEGHOLOK_02271	7.2e-174	-	-	-	-	-	-	-	-
NEGHOLOK_02272	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NEGHOLOK_02273	2.18e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NEGHOLOK_02274	3.12e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEGHOLOK_02275	5.49e-206	-	-	-	S	ko:K03453	-	ko00000	Bile acid
NEGHOLOK_02278	6.39e-71	-	-	-	-	-	-	-	-
NEGHOLOK_02279	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEGHOLOK_02280	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
NEGHOLOK_02281	1.39e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
NEGHOLOK_02282	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
NEGHOLOK_02283	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
NEGHOLOK_02285	1.2e-49	-	-	-	-	-	-	-	-
NEGHOLOK_02286	2.33e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
NEGHOLOK_02287	1.61e-183	-	-	-	-	-	-	-	-
NEGHOLOK_02288	7.43e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
NEGHOLOK_02290	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
NEGHOLOK_02291	7.13e-301	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
NEGHOLOK_02292	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NEGHOLOK_02293	7.36e-220	-	-	-	K	-	-	-	Transcriptional regulator
NEGHOLOK_02294	5.74e-176	-	-	-	C	-	-	-	aldo keto reductase
NEGHOLOK_02295	2.06e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NEGHOLOK_02296	5.85e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
NEGHOLOK_02297	1.67e-309	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
NEGHOLOK_02298	1.03e-159	-	-	-	IQ	-	-	-	Short chain dehydrogenase
NEGHOLOK_02299	9.61e-28	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NEGHOLOK_02301	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
NEGHOLOK_02303	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
NEGHOLOK_02304	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NEGHOLOK_02306	2.57e-170	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NEGHOLOK_02307	3.88e-308	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
NEGHOLOK_02309	1.15e-05	-	-	-	-	-	-	-	-
NEGHOLOK_02311	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NEGHOLOK_02312	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
NEGHOLOK_02313	8.94e-56	-	-	-	-	-	-	-	-
NEGHOLOK_02314	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
NEGHOLOK_02315	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
NEGHOLOK_02316	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
NEGHOLOK_02324	1.37e-40	-	-	-	S	-	-	-	TIR domain
NEGHOLOK_02327	6.72e-102	-	-	-	S	-	-	-	Terminase
NEGHOLOK_02329	1.02e-76	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
NEGHOLOK_02333	9.53e-31	-	-	-	M	-	-	-	lytic transglycosylase activity
NEGHOLOK_02335	5.36e-09	-	-	-	-	-	-	-	-
NEGHOLOK_02342	6.21e-39	-	-	-	-	-	-	-	-
NEGHOLOK_02343	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEGHOLOK_02345	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
NEGHOLOK_02346	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
NEGHOLOK_02347	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_02348	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
NEGHOLOK_02349	2.27e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
NEGHOLOK_02350	5.74e-211	ybfH	-	-	EG	-	-	-	spore germination
NEGHOLOK_02351	9.28e-139	-	-	-	-	-	-	-	-
NEGHOLOK_02352	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NEGHOLOK_02353	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEGHOLOK_02354	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
NEGHOLOK_02357	3.56e-234	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
NEGHOLOK_02360	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
NEGHOLOK_02362	2.53e-106	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
NEGHOLOK_02364	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NEGHOLOK_02365	1.85e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEGHOLOK_02366	3.4e-227	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
NEGHOLOK_02367	8.31e-254	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
NEGHOLOK_02373	5.05e-34	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
NEGHOLOK_02374	2.46e-133	-	-	-	S	-	-	-	Terminase
NEGHOLOK_02380	3.94e-200	-	-	-	L	-	-	-	AAA domain
NEGHOLOK_02382	2.66e-59	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
NEGHOLOK_02383	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
NEGHOLOK_02384	5.54e-30	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02385	6.44e-72	rpiA	5.3.1.6	-	GK	ko:K01807,ko:K02444	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko03000	Replication initiator protein A (RepA) N-terminus
NEGHOLOK_02386	1.33e-14	-	-	-	-	-	-	-	-
NEGHOLOK_02387	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
NEGHOLOK_02388	3.34e-232	-	-	-	T	-	-	-	GHKL domain
NEGHOLOK_02389	6.02e-171	-	-	-	T	-	-	-	cheY-homologous receiver domain
NEGHOLOK_02390	1.71e-75	-	-	-	-	-	-	-	-
NEGHOLOK_02396	1.73e-50	-	-	-	-	-	-	-	-
NEGHOLOK_02397	5.61e-123	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
NEGHOLOK_02398	0.0	-	-	-	L	-	-	-	Reverse transcriptase
NEGHOLOK_02399	4.15e-17	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
NEGHOLOK_02400	3.12e-217	-	-	-	-	-	-	-	-
NEGHOLOK_02401	3.82e-168	-	-	-	-	-	-	-	-
NEGHOLOK_02402	2.07e-60	-	-	-	-	-	-	-	-
NEGHOLOK_02403	2.01e-243	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
NEGHOLOK_02404	8.31e-82	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02407	3.11e-69	-	-	-	-	-	-	-	-
NEGHOLOK_02413	8.57e-153	-	-	-	-	-	-	-	-
NEGHOLOK_02417	5.37e-50	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
NEGHOLOK_02421	1.6e-40	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02422	7.84e-128	-	-	-	D	-	-	-	Plasmid recombination enzyme
NEGHOLOK_02423	1.97e-70	-	-	-	L	-	-	-	Protein of unknown function (DUF3849)
NEGHOLOK_02424	4.35e-144	-	-	-	M	-	-	-	SpoVG
NEGHOLOK_02425	2.15e-203	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NEGHOLOK_02427	3.05e-200	-	-	-	L	ko:K02315	-	ko00000,ko03032	Psort location Cytoplasmic, score
NEGHOLOK_02428	1.39e-32	-	-	-	S	-	-	-	Transposon-encoded protein TnpW
NEGHOLOK_02429	6.12e-193	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NEGHOLOK_02430	1.84e-167	-	-	-	U	-	-	-	AAA domain
NEGHOLOK_02434	8.28e-162	-	-	-	K	-	-	-	LytTr DNA-binding domain
NEGHOLOK_02435	2.13e-239	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
NEGHOLOK_02436	2.71e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NEGHOLOK_02437	7.98e-136	-	-	-	L	-	-	-	Helix-turn-helix domain of transposase family ISL3
NEGHOLOK_02438	2.33e-306	-	-	-	L	-	-	-	Transposase DDE domain
NEGHOLOK_02439	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
NEGHOLOK_02441	3.81e-149	repA	-	-	GK	-	-	-	Replication initiator protein A (RepA) N-terminus
NEGHOLOK_02442	6.39e-89	-	-	-	S	-	-	-	Cysteine-rich VLP
NEGHOLOK_02443	4.72e-67	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02444	9.14e-84	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
NEGHOLOK_02445	1.55e-126	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
NEGHOLOK_02447	6.66e-05	-	-	-	-	-	-	-	-
NEGHOLOK_02449	7.67e-100	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
NEGHOLOK_02450	1.29e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_02451	2.72e-42	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02452	8.89e-299	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
NEGHOLOK_02455	1.52e-64	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
NEGHOLOK_02456	9.21e-38	-	-	-	L	-	-	-	Single-strand binding protein family
NEGHOLOK_02457	1.2e-77	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02458	4.84e-175	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEGHOLOK_02459	1.24e-11	-	-	-	K	-	-	-	Helix-turn-helix domain
NEGHOLOK_02461	2.49e-182	repA	-	-	GK	-	-	-	Replication initiator protein A (RepA) N-terminus
NEGHOLOK_02464	9.12e-70	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
NEGHOLOK_02468	1.45e-35	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
NEGHOLOK_02471	1.35e-162	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEGHOLOK_02472	2.38e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF4314)