Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 27 | 32 | 41.87 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| DKGCIGHF_62 | 59529 | 60398 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| DKGCIGHF_62 | 60398 | 60991 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| DKGCIGHF_116 | 22131 | 23390 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681445 |
| DKGCIGHF_116 | 18333 | 19109 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 99.87 | 100.00 | WP_011681440 |
| DKGCIGHF_62 | 60398 | 60991 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| DKGCIGHF_116 | 17066 | 18214 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_011681439 |
| DKGCIGHF_62 | 60398 | 60991 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| DKGCIGHF_116 | 21158 | 22134 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| DKGCIGHF_116 | 16128 | 17069 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011681438 |
| DKGCIGHF_51 | 1162 | 2001 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| DKGCIGHF_70 | 65510 | 67168 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| DKGCIGHF_116 | 15322 | 16128 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011681437 |
| DKGCIGHF_116 | 17066 | 18214 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 99.48 | 100.00 | WP_011227431 |
| DKGCIGHF_116 | 16128 | 17069 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.47 | 100.00 | WP_011227430 |
| DKGCIGHF_116 | 10969 | 12714 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 99.37 | 100.00 | WP_011681434 |
| DKGCIGHF_116 | 19455 | 20170 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 99.30 | 99.86 | WP_011681442 |
| DKGCIGHF_116 | 20172 | 21140 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| DKGCIGHF_116 | 15322 | 16128 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.26 | 100.00 | WP_011227429 |
| DKGCIGHF_62 | 24870 | 25631 | srtA | 0.0 | Sortase A | Exoenzyme | 99.08 | 100.00 | - |
| DKGCIGHF_75 | 13834 | 14565 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011681176 |
| DKGCIGHF_75 | 13834 | 14565 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011226048 |
| DKGCIGHF_116 | 23509 | 24360 | rfbD | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_014621820 |
| DKGCIGHF_75 | 13834 | 14565 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011227248 |
| DKGCIGHF_116 | 10969 | 12714 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 98.05 | 100.00 | WP_011227426 |
| DKGCIGHF_103 | 111 | 900 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.98 | 99.75 | - |
| DKGCIGHF_106 | 655 | 2070 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681165 |
| DKGCIGHF_75 | 15276 | 16016 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.44 | 99.87 | WP_011681174 |
| DKGCIGHF_75 | 12373 | 13833 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.33 | 100.00 | WP_011681177 |
| DKGCIGHF_75 | 15276 | 16016 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.03 | 99.87 | WP_011226046 |
| DKGCIGHF_75 | 14574 | 15266 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.83 | 99.86 | WP_011226047 |
| DKGCIGHF_75 | 15276 | 16011 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.74 | 98.00 | WP_011227246 |
| DKGCIGHF_75 | 14574 | 15266 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.54 | 100.00 | WP_011227247 |
| DKGCIGHF_75 | 12373 | 13833 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.03 | 100.21 | WP_011226049 |
| DKGCIGHF_75 | 12373 | 13833 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.55 | 100.21 | WP_041827043 |
| DKGCIGHF_75 | 16073 | 17438 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.46 | 99.85 | WP_011681173 |
| DKGCIGHF_75 | 16073 | 17440 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.08 | 100.00 | WP_011226045 |
| DKGCIGHF_75 | 14574 | 15266 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011681175 |
| DKGCIGHF_11 | 90778 | 92081 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| DKGCIGHF_47 | 297 | 1307 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.66 | 99.90 | WP_002986042 |
| DKGCIGHF_116 | 14099 | 15322 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.92 | 99.92 | WP_012000441 |
| DKGCIGHF_116 | 15322 | 16128 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 83.27 | 100.00 | WP_012000440 |
| DKGCIGHF_108 | 2254 | 3537 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| DKGCIGHF_62 | 61420 | 62466 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| DKGCIGHF_116 | 14585 | 15322 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 96.61 | 61.35 | WP_011227428 |
| DKGCIGHF_116 | 14585 | 15322 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 96.34 | 61.35 | WP_011681436 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| DKGCIGHF_62 | 22183 | 21200 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.51 | 100.00 | AAK75326 |
| DKGCIGHF_91 | 14018 | 12945 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| DKGCIGHF_80 | 66884 | 69187 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| DKGCIGHF_11 | 7095 | 8063 | spr0084 | 0.0 | pathogenitcity related | 92.26 | 98.48 | AAK98888 |
| DKGCIGHF_65 | 46339 | 47820 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| DKGCIGHF_35 | 27658 | 25412 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| DKGCIGHF_51 | 22013 | 23011 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| DKGCIGHF_79 | 27 | 998 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| DKGCIGHF_116 | 73752 | 72601 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| DKGCIGHF_116 | 37534 | 35546 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| DKGCIGHF_62 | 38381 | 40111 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.22 | 100.00 | AAK34199 |
| DKGCIGHF_78 | 7000 | 8478 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| DKGCIGHF_11 | 90778 | 92079 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| DKGCIGHF_78 | 21735 | 23627 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| DKGCIGHF_35 | 22487 | 24196 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| DKGCIGHF_46 | 19146 | 20156 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| DKGCIGHF_70 | 30294 | 31655 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| DKGCIGHF_46 | 69461 | 67569 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| DKGCIGHF_11 | 76339 | 77229 | bglB | 8.41e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| DKGCIGHF_57 | 11809 | 10874 | SP_0676 | 2.02e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| DKGCIGHF_35 | 25220 | 24363 | metF | 2.84e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| DKGCIGHF_22 | 18577 | 19281 | covR | 5.38e-132 | responder protein | 85.11 | 100.00 | AAK71319 |
| DKGCIGHF_65 | 27365 | 26694 | rr01 | 9.58e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| DKGCIGHF_22 | 18577 | 19281 | walR | 3.21e-122 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| DKGCIGHF_35 | 18533 | 17865 | CiaR | 3.26e-122 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| DKGCIGHF_35 | 18533 | 17862 | ciaR | 3.89e-120 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| DKGCIGHF_59 | 16140 | 16826 | CovR | 3.91e-120 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| DKGCIGHF_51 | 23287 | 23661 | SpxA2 | 1.48e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| DKGCIGHF_74 | 25593 | 25306 | spr0479 | 3.00e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| DKGCIGHF_82 | 9893 | 9639 | spr1327 | 5.99e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| DKGCIGHF_50 | 31393 | 31656 | spr0175 | 1.97e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| DKGCIGHF_50 | 32196 | 32486 | spr0177 | 1.43e-37 | essential gene | 81.00 | 98.02 | AAK98981 |
| DKGCIGHF_108 | 3695 | 4195 | RopE (M5005_Spy_1611) | 2.28e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| DKGCIGHF_80 | 66884 | 69181 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| DKGCIGHF_46 | 55008 | 53989 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| DKGCIGHF_3 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_9 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_10 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_11 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_14 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_22 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_27 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_30 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_33 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_35 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_44 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_45 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_46 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_47 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_49 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_50 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_51 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_53 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_54 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_55 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_56 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_57 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_58 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_59 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_60 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_61 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_62 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_63 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_64 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_65 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_66 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_67 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_68 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_69 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_70 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_71 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_72 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_73 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_74 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_75 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_77 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_78 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_79 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_80 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_81 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_82 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_84 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_85 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_88 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_89 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_90 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_91 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_93 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_94 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_97 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_98 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_99 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_100 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_101 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_103 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_104 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_106 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_107 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_108 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_109 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_111 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_113 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_114 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_116 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_117 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_119 | 1.0 | 0.0 | 1.0 |
| DKGCIGHF_121 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_127 | 0.0 | 1.0 | 0.0 |
| DKGCIGHF_129 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)